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Abstract #1170

Comparison of Oscillating Steady State to GRE BOLD for fMRI

Shouchang Guo1 and Douglas C. Noll2

1Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Ann Arbor, MI, United States, 2Biomedical Engineering, University of Michigan, Ann Arbor, Ann Arbor, MI, United States

The combination of a quadratic phase sequence with balanced gradients leads to an oscillating steady state (OSS) MRI signal with an average signal amplitude that is 2-3 times the Ernst angle GRE imaging. With signal phase varies with off-resonance making the resultant signal T2*-weighted and thus, suitable for BOLD fMRI. In this work, simulations of changes to the tissue T2*, as seen in fMRI, are carried out for OSS and compared to GRE. The OSS method is compared to GRE for high-resolution fMRI studies, demonstrating substantially higher activation counts as well as temporal SNR (tSNR).

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