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Abstract #1253

Dictionary-Based Oscillating Steady State fMRI Reconstruction

Shouchang Guo1, Douglas C. Noll2, and Jeffrey A. Fessler1

1Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, United States, 2Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States

Oscillating steady state (OSS) imaging is a new fMRI acquisition method that substantially improves SNR by exploiting a large and oscillating signal. However, the oscillation nature of the signal leads to an increased number of acquisitions. To improve the temporal resolution and address the nonlinearity of the OSS signal, we propose a novel dictionary-based regularization method for OSS reconstruction to reconstruct dramatically undersampled (e.g. R = 12) data. The proposed method leads to better image quality than CG-SENSE and does not require any temporal filtering like low-rank methods, therefore the undersampling directly leads to an improved fMRI temporal resolution. The high SNR advantage of OSS is also well preserved.

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