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Abstract #1268

Evaluation of inter- and intramuscular differences using multi-slice T2* measurements after an in-magnet stepping exercise.

Thom T. J. Veeger1, Celine Baligand1, Andrew Webb1, Jurriaan H. de Groot2, and Hermien E. Kan1

1Radiology, Leiden University Medical Center, Leiden, Netherlands, 2Rehabilitation, Leiden University Medical Center, Leiden, Netherlands

In this study we explored the feasibility of using an MR-compatible ergometer mimicking stair climbing to study differences in T2* after exercise between and within different thigh muscles. Four healthy subjects performed a 10-minute stepping exercise inside a 3T. Participants exercised at either a high rate of perceived exertion (RPE) or a low RPE. Clear differences between low and high RPE and different muscles, but not within muscles, were found. This shows that it is possible to use stair-climbing using an MR-compatible ergometer to study differences between and within muscles in response to exercise.

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