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Abstract #1291

Diffusion-Weighted MRI in Juvenile Osteochondritis Dissecans (JOCD) at 3T

Kai D. Ludwig1, Casey P. Johnson1,2, Stefan Zbyn1,2, Takashi Takahasi2, Shelly Marette2, Bradley J. Nelson3, Marc A. Thompkins3, Cathy S. Carlson4, and Jutta M. Ellermann1,2

1Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, MN, United States, 2Radiology, University of Minnesota, Minneapolis, MN, United States, 3Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, United States, 4Veterinary Clinical Sciences, University of Minnesota, St. Paul, MN, United States

Diffusion-weighted MRI (DWI) may help elucidate the etiology and progression of juvenile osteochondritis dissecans (JOCD) by probing tissue/cellular characteristics of JOCD lesions and the underlying parent bone. In this study, we observed elevated DWI signal and increased apparent diffusion coefficient (ADC) values within and proximal to OCD lesions compared to surrounding bone marrow and control sites. ADC values within the lesion and the parent bone may help distinguish healing from non-healing lesions, thereby improving prognostication of JOCD and clinical decision making.

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