Abstract #1317

Quantitative hip cartilage MRI of patients with hip dysplasia: Evaluation of dGEMRIC, T1ρ and T2* mapping

Gerd Melkus^1,2, Paul E Beaulé^3,4, Geoffrey Wilkin^3,4, and Kawan Rakhra^1,2

¹Medical Imaging, The Ottawa Hospital, Ottawa, ON, Canada, ²Radiology, University of Ottawa, Ottawa, ON, Canada, ³Division of Orthopaedic Surgery, The Ottawa Hospital, Ottawa, ON, Canada, ⁴Medicine, University of Ottawa, Ottawa, ON, Canada

Developmental dysplasia of the hip is a common risk factor of early osteoarthritis. Knowledge of the molecular health of cartilage using quantitative MR methods could diagnose and stage the disease and may also allow for treatment stratification. In this study, we evaluated and compared three different biochemical sensitive MR methods (dGEMRIC, T1ρ and T2*) for cartilage imaging on patients with developmental dysplasia of the hip. Quantitative T1ρ as well as T2* mapping of the hip cartilage correlated significantly with the dGEMRIC method and could possibly replace the contrast-based method.

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