Abstract #1332

Rapid Quantitative Simultaneous Bilateral Knee Imaging with Fully Automated Femoral Cartilage Analysis: Toward Knee Asymmetry Evaluation.

Marco Barbieri^1,2, Arjun D. Desai², Feliks Kogan², Valentina Mazzoli², Elka Rubin², Gastone Castellani¹, Garry E. Gold^2,3, Brian A. Hargreaves^2,3,4, and Akshay S. Chaudhari²

¹Department of Physics and Astronomy, University of Bologna, Bologna, Italy, ²Department of Radiology, Stanford University, Stanford, CA, United States, ³Department of Bioengineering, Stanford University, Stanford, CA, United States, ⁴Department of Electrical Engineering, Stanford University, Stanford, CA, United States

Quantitative bilateral knee MRI and whole femoral cartilage analysis is currently limited by costs and scan time. We propose a rapid, simultaneous bilateral knee MRI protocol followed by a fully automated pipeline to perform quantitative T2 analysis of the whole femoral cartilage plate of both knees. Five healthy subjects and a subject with an ACL reconstruction were scanned in this study and the results demonstrated high scan-rescan repeatability and a good agreement between manual and automatic segmentation. The proposed acquisition method with automated analysis may make bilateral imaging more feasible and efficient for use in longitudinal and cross-sectional studies.

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