Many myeloproliferativediseases,e.g., anemia and acute leukemia, impair microstructure of bone marrow. However, it is unclear the relationship between parameters of IVIM and microstructure of bone marrow (cellullarity, and microvessel density).Texture analysis was performed on D, D* and fmaps of the spinal bone marrow extracted from IVIM MRI on 48 patients (28 patients with acute leukemia and 20 patients with anemia). Bone marrow cellularity and MVD were significantly different between two groups. The f values in group of acute leukemia were significantly higher than that of anemia . The texture parameters of D, D* and f mapping has potential to reveal heterogeneous feature of microstructure in bone marrow.