There is an increasing clinical need for improving early diagnosis and evaluation of early response after interventions and treatment in musculoskeletal disorders. Quantitative MRI is a promising tool towards these goals. However, quantifying relaxation times normally requires long acquisition time and is prone to B0 and B1 inhomogeneity and other imperfections. Moreover, it is difficult to optimize the acquisition parameters of conventional relaxation time imaging sequences to provide accurate T1 and T2 quantifications with a large range. MR fingerprinting (MRF) is a recently developed technique, which enables fast imaging and quantification of multiple tissue parameters simultaneously, and shows promising results in neural, body and cardiac imaging. However, the application of MRF to MSK imaging is very limited. The goal of this study was to demonstrate the feasibility and quantification repeatability of MRF in knee joints.