The MRI-based Radiomics of pancreas can identify several imaging-characteristics (e.g. texture, shape, signal intensity, etc.) that are distinct in healthy and cancerous pancreas. We performed MRI-based radiomics of pancreas to demonstrate that radiomics play an important rule to differentiate healthy and cancerous pancreas and can assist diagnosis and management of PC. Multiple statistical tests demonstrated that 18% of the total 250 radiomic features were significantly different between healthy and cancerous pancreas. These features have high diagnostic accuracy to detect PC. We conclude that MRI-based radiomics of pancreas can potentially have a future role in early detection, prognosis, and prediction of treatment outcome of PC.