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Abstract #1671

Quantitative dynamic contrast-enhanced magnetic resonance imaging as a potential tool for preoperative predicting the response to neoadjuvant chemotherapy in locally advanced gastric adenocarcinoma

Yongjian Zhu1, Ying Li1, Jun Jiang1, Wen Zhang2, Liming Jiang1, and Lizhi Xie3

1Department of Imaging Diagnosis, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 3GE healthcare, China, Beijing, China

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has been applied in diagnosis of different cancers, however its potential in gastric cancer has not been fully explored. In this study, we research into the value of DCE-MRI parameters in evaluating the response to chemotherapy in gastric cancer. It was found that the Ktrans and Ve values showed good predictive performance through distinguishing responders from non-responders, which could provide effective technical assistance for the choice of clinical treatment.

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