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Abstract #1737

Evaluation of Fontan Associated Liver Disease (FALD) with MRI: Does cardiac function play a role?

Kathan A Amin1, Liisa Bergmann1, Alejandro Roldan1, Scott B Reeder2, and Christopher J Francois1

1Radiology, University of Wisconsin - Madison, MADISON, WI, United States, 2Radiology, Medical Physics, Biomedical Engineering, Medicine, Emergency Medicine, University of Wisconsin - Madison, MADISON, WI, United States

The Fontan procedure prolongs survival in patients with congenital heart disease with mono-ventricle physiology but is associated with multiple long-term complications, including Fontan associated liver disease (FALD). The pathophysiology of FALD is poorly understood. In this study, the relationship between ventricular ejection fraction (EF) and FALD was investigated through a retrospective review of 24 Fontan patients who underwent cardiac and liver MRI. No correlation was identified between systemic ventricular EF and liver stiffness. This demonstrates the need for further investigation into the pathophysiology of FALD. Potential exploration may include flow related differences, or variations in systemic venous pressures.

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