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Abstract #1793

The magnetic resonance elastography of liver for patients with Gaucher disease after enzyme replacement therapy

Di Li1, Yang Fan2, juan xiao tao1, and Yun Peng1

1Beijing Children's Hospital, Capital Medical University, Beijing, China, 2GE Healthcare China, Beijing, China

Gaucher disease (GD) is one of the most prevalent lysosomal storage disorders, which may lead to long term liver complications including fibrosis and cirrhosis. At present, enzyme replacement therapy (ERT) is widely used for GD in clinic.Magnetic resonance elastography (MRE) is the most accurate noninvasive technique for detection and staging of liver fibrosis.No significant difference was detected for GD patients after ERT in this study. It may indicate that enzyme replacement therapy is effective for most patients.

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