Diffusion-weighted imaging has been shown useful in measuring liver apparent diffusion coefficient (ADC) that can provide valuable information for clinical diagnosis. Single-shot diffusion-weighted echo-planar imaging (ssDW-EPI) is the preferred acquisition technique for ADC measurement on clinical MRI scanner. Recently, a multiplexed sensitivity encoding (MUSE) framework has been developed to reconstruct high-quality multi-shot DW-EPI (msDW-EPI) image in brain. In this study, we aim to evaluate the msDW-EPI technique on liver ADC measurement by quantitatively comparing measured ADC values obtained from either msDW-EPI or ssDW-EPI.
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