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Abstract #1892

Comparison of Capabilities for Pulmonary Functional Loss Evaluation and Clinical Stage Classification between 3D Oxygen-Enhanced MRI at 3T System and Thin-Section CT in Smokers

Yoshiharu Ohno1,2, Masao Yui3, Takeshi Yoshikawa1,2, Shinichiro Seki1,2, Katsusuke Kyotani4, and Takamichi Murakami4,5

1Division of Functional and Diagnostic Imaging Research, Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan, 2Advanced Biomedical Imaging Research Center, Kobe University Graduate School of Medicine, Kobe, Japan, 3Canon Medical Systems Corporation, Otawara, Japan, 4Center for Radiology and Radiation Oncology, Kobe University Hospital, Kobe, Japan, 5Division of Radiology, Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan

Recently, 3D O2-enhanced MRI at 3T system is recently developed by Cannon Medical Systems Corporation. On the other hands, no one directly compare this technique with quantitatively assessed CT for smoking-related COPD assessment. We hypothesized that 3D O2-enhanced MRI has a potential for quantitative assessment of morphological changes due to smoking-related COPD as well as quantitatively assessed thin-section CT. The purpose of this study was to prospectively and directly compare the quantitative capability for pulmonary functional loss assessment and clinical stage classification between 3D O2-enhanced MRI and thin-section CT in smokers.

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