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Abstract #1982

Pulmonary Artery 3D Wall Shear Stress is Lower in Patients with WHO Group 2 Pulmonary Hypertension

Michael Scott1, Daniel Z Gordon1, Mohammed Elbaz1, Vamsi Reddy1, Jeremy D Collins2, Benjamin Freed1, Sanjiv Shah1, Michael Cuttica1, Michael Markl1, and James C Carr1

1Northwestern University, Chicago, IL, United States, 2Mayo Clinic, Rochester, MN, United States

Patients with pulmonary hypertension (PHTN) are known to have altered pulmonary artery (PA) hemodynamics in addition to differing PA pressures measured using invasive right heart catherization. 4D flow MRI can provide information about PA hemodynamics, such as 3D wall shear stress that might be useful in diagnosis or grading of PHTN. Previous work on WSS used manually placed planes for evaluating regional WSS, we derive WSS metrics over the entire vessel. 3D WSS measurements in the PA were significantly different between a cohort of patients with WHO group 2 PHTN and healthy controls and were correlated with catheter-based pressure measurements.

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