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Abstract #2015

Accelerating modified Look-Locker inversion recovery (MOLLI): Shortened inversion-recovery-based myocardial T1 mapping schemes

Li Huang1, Radhouene Neji1,2, Muhammad Sohaib Nazir1, John Whitaker1, Filippo Bosio1, Amedeo Chiribiri1, Reza Razavi1, and S├ębastien Roujol1

1School of Biomedical Engineering and Imaging Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

Abnormal native myocardial T1 times are associated with a variety of cardiomyopathies, and are widely measured by inversion-recovery-based myocardial T1 mapping techniques such as modified Look-Locker inversion recovery (MOLLI). These sequences are limited in patients with severe breathholding difficulties for relatively long duration of breathholds. In this work, we sought to develop and characterize shortened schemes using less amount of T1-weighted images to reduce their sensitivity to imperfect breathholds.

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