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Abstract #2035

Rapid cardiac diffusion-weighted imaging with novel motion-compensated spherical tensor encoding

Irvin Teh1, Filip Szczepankiewicz2,3,4, Erica Dall’Armellina1, Sven Plein1, Markus Nilsson2, and Jürgen E. Schneider1,5

1Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom, 2Clinical Sciences, Lund University, Lund, Sweden, 3Harvard Medical School, Boston, MA, United States, 4Brigham and Women's Hospital, Boston, MA, United States, 5Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom

Cardiac diffusion-weighted imaging (CDWI) is an emerging method for non-invasive assessment of cardiac microstructure. In CDWI, averaging and triggering are routinely used to mitigate motion artefacts, which results in long acquisition times. We have developed a novel motion-compensated spherical tensor encoding technique that reduces the acquisition time by a factor of up to three. Quantitatively, the method yields similar mean diffusivity as conventional methods, but enables accurate measurements in less than a minute.

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