Internal carotid artery stenosis is a major source of ischemic stroke. Assessment of plaque formation and longitudinal progression necessitates reproducibility of imaging and post-processing methods. In this study, preliminary results on the reproducibility of wall thickness measurements using 3D multi-contrast vessel wall imaging at two different time points in healthy volunteers are presented. Between the two exams, relative deviations of the vessel wall thickness were mostly below 10% and below 15% when comparing different sequences. In conclusion, reproducible assessment of the carotid arteries with multi-contrast vessel wall imaging is feasible.