Abstract #2111

Four-dimensional whole-heart cine imaging with isotropic resolution in one single breath-hold: initial results

Davide Piccini^1,2,3, Lorenzo Di Sopra², Jérôme Yerly^2,4, Gabriella Vincenti⁵, Tobias Rutz⁵, Juerg Schwitter⁵, and Matthias Stuber^2,4

¹Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ²Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ³LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁴Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, ⁵Division of Cardiology and Cardiac MR Center, University Hospital of Lausanne (CHUV), Lausanne, Switzerland

In cardiac MRI, the evaluation of left ventricular ejection fraction (LVEF) is based on well-defined protocols and involves a stack of 2D cine images acquired during multiple breath-holds. This procedure is time-consuming and may result in suboptimal coverage and inter-slice misregistration. Here, a novel acquisition protocol for 3D cine imaging with whole-heart coverage in one single breath-hold with isotropic spatial resolution is described and tested in 10 subjects in comparison to the 2D gold-standard. All 2D datasets and 9/10 3D datasets were considered adequate for LVEF calculation. Bland-Altman analysis of LVEF shows good agreement and no bias between the two measurements.

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