The idea of defining a biomarker to assess the progression of Nonalcoholic Fatty Liver Disease (NAFLD) by using Magnetic Resonance Spectroscopy (MRS) emerges due to the need to find a way to replace biopsy with a non-invasive method. The purpose of this study is to investigate the composition of the liver fatty acids based in the metabolite signals in MRS in NAFLD mice fed with a western-diet at 3 time-point during the progression of the disease. Our findings showed significant changes in the diallylic (2.8 ppm), olefinic (5.3ppm), allilic (2.0 ppm) and bulk methylene (1.3 ppm) peaks during the progression of the NAFLD by using high-resolution MRS.
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