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Abstract #2313

Association between Metabolism Measured by PET/CT and Vascular Parameters Measured by Dynamic Contrast Enhanced MRI in Spinal Lesions

Jiahui Zhang1, Enlong Zhang1, Yanyan Zhang2, Yongye Chen1, Ning Lang1, Hon J Yu3, Huishu Yuan1, and Min-Ying Lydia Su3

1Department of Radiology, Peking University Third Hospital, Beijing, China, 2Department of Nuclear Medicine, Peking University Third Hospital, Beijing, China, 3Department of Radiological Sciences, University of California, Irvine, CA, United States

A total of 49 patients with spinal lesions receiving DCE-MRI and 18F-FDG PET/CT were analyzed. The ROI was manually placed on strongly enhanced area on MRI to measure DCE enhancement kinetics, and from which the wash-in and maximum enhancement ratio, wash-out slope, Ktrans and kep were extracted. SUVmax was measured from the corresponding lesion on FDG uptake map. The results showed that vascular parameters measured from DCE-MRI were not correlated with glucose metabolism measured by PET/CT; therefore, they represent different aspects of lesion, and may be combined for better staging or predicting prognosis rather than being used for diagnosis.

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