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Abstract #2323

PET/MRI versus PET/CT in Oncology: A Prospective Single-center Study Focusing on Implications for Patient Management and Cost Considerations

Marius Erik Mayerhoefer1,2, Helmut Prosch3, Lucian Beer3, Dietmar Tamandl3, Thomas Beyer3, Ivo Rausch3, Dominik Berzaczy3, Markus Raderer3, Christoph Hoeller3, Matthias Preusser3, Ahmed Ba-Ssalamah3, Georgios Karanikas3, Julia Kesselbacher3, Gerald Prager3, Michael Weber3, Bernhard Brauner4, Markus Mitterhauser3, Harald Eidherr3, and Alexander Haug3

1Medical University of Vienna, Wien, Austria, 2Memorial Sloan Kettering Cancer Center, New York, NY, United States, 3Medical University of Vienna, Vienna, Austria, 4Siemens Healthineers, Vienna, Austria

To prospectively investigate the clinical impact of PET/MRI, compared to PET/CT, in a mixed population of cancer patients, and to perform an economic evaluation of PET/MRI. 263 patients (330 same-day PET/CT and PET/MRI examinations) were analyzed. PET/MRI was accurate in 319/330 examinations, and PET/CT in 277/330 examinations; respective accuracies (97.3% vs. 83.9%) differed significantly (P<0.001). Additional findings on PET/MRI had implications for clinical management in 21/263 patients (8.0%). Incremental cost-effectiveness ratios for PET/MRI were 22.47 EUR (~26.28 USD) per percent of diagnostic accuracy, and 37.64 EUR (~44.06 USD) per percent of correctly managed patients.

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