Quantifying physical properties of sodium could be of benefit to assess more specifically changes in cellular homeostasis accompanying neuroinflammatory or neurodegenerative processes. Here, we performed whole-brain Quantitative Imaging using Configuration States (QuICS) in vivo at 7 Tesla to assess simultaneously Total Sodium Concentration (TSC) and relaxation times (T1 and T2). An acquisition time of 20 minutes was sufficient for a 10 mm3 isotropic resolution. In the future, the use of non-Cartesian trajectories could further reduce the overall acquisition time, opening the way to the additional estimation of the trace apparent diffusion coefficient.
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