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Abstract #2668

Correlation of cerebrovascular reserve assessed by acetazolamide-stress SPECT with collaterals on arterial spin-labeling MRI in patients with carotid occlusive disease

Hyunkoo Kang1 and Yoone Kim1

1Seoul Veterans Hospital, Seoul, Korea, Republic of

We evaluated the correlation between cerebrovascular reserve (CVR) on acetazolamide (ACZ) -stress SPECT brain scans and collaterals on ASL MRI in ICA stenosis. 86 patients with ICA stenosis (>70%) were enrolled in this study. On ASL, late-arriving flow appears as serpiginous high ASL signal within cortical vessels, which has been termed arterial transit artifact (ATA). 82/86 ICA stenosis patients underwent SPECT imagings with Tc-99m-ECD in the resting and after ACZ challenge. Significant positive relationship was observed between normal CVR group and ATA showing group in ICA stenosis patients on ASL brain perfusion (p=0.035, chi-square test).

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