Dopamine is a neurotransmitter that plays an important role in psychosis. Neuromelanin is a by-product of the synthesis of dopamine. In First Episode of Psychosis (FEP) is reported the effect that causes dopamine and its relationship with neuromelanin. However, it has not been reported signal change due to accumulation of heavy metal using magnetic resonance imaging techniques. We found susceptibility changes in two areas of brain using QSM, the left subthalamic nucleus and right caudate. This finding might help to discriminate between FEP patients and healthy subjects.