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Abstract #2871

A predictive model for postlaminar optic nerve invasion in retinoblastoma  basedon radiomic features from MR images

Zhenzhen Li1, Jian Guo1, and Junfang Xian1

1Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, Beijing, China

Retinoblastomas (RB) with postlaminar optic nerve invasion (PLONI) increases the risk for systemic metastasis or local recurrence. MRI is the only method to detect the PLONI in patients with eye-saving treatment strategies. But accuracy of MRI in identifying PLONI was relatively limited. Radiomics is an emerging field with a number of different uses being proposed. We hypothesized that radiomics can have an additional contribution to predicting PLONI in patients with retinoblastoma. This study validated our hypothesis.

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