The use of complimentary imaging modalities in the glioma management of individual patients can provide additional information for further treatment strategy. In view of the limitations of anatomical imaging, cumbersome radio labeling procedures of PET tracers with amino-acids, in the present study, we have performed multimodality imaging using 99mTc-methionine SPECT (as cost effective substitute for expensive amino acid PET imaging), perfusion MRI and MRS for the the differentiation of radiation necrosis from recurrent/residual glioma by the means of serial imaging.
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