Meeting Banner
Abstract #2915

Volume of anisotropic diffusion abnormality as prognostic imaging marker in treated glioblastoma patients

Bart Roelf Jan van Dijken1, Chao Li2,3, Peter Jan van Laar1, Shuo Wang4,5, Stephen J Price2, and Anouk van der Hoorn1,2

1Radiology, Medical Imaging Center (MIC), University Medical Center Groningen, University of Groningen, Groningen, Netherlands, 2Brain Tumour Imaging Group, Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke’s hospital, University of Cambridge, Cambridge, United Kingdom, Cambridge, United Kingdom, 3Department of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China, Shanghai, China, 4Department of Radiology, University of Cambridge, Cambridge, UK, Cambridge, United Kingdom, 5The Centre for Mathematical Imaging in Healthcare, Department of Pure Mathematics and Mathematical Statistics, University of Cambridge, Cambridge, United Kingdom

The purpose of this study was to investigate the prognostic value of anisotropic diffusion abnormality in 30 treated glioblastoma patients. Diffusion tensor imaging was performed after chemoradiotherapy and volumes of diffusion abnormalities were extracted. Our results showed that a larger volume of high anisotropic abnormality was associated with worsened patient survival. Anisotropic diffusion can therefore potentially be employed as a prognostic imaging marker in longitudinal management of glioblastoma patients.

This abstract and the presentation materials are available to members only; a login is required.

Join Here