MRI is widely involved for the diagnosis of brain tumors, and offers qualitative assessment of the tumor with regard to the surrounding brain tissues. However, not only visual inspections may introduce subjective bias, there may be cases that pose challenges for diagnosis even with the use of contrast agent. In this work, a novel relaxation quantification approach named synthetic MRI was applied to 40 patients with glioma or meningioma. Our data showed that both T1 and T2 values of glioma were significant higher than that of meningioma. indicating that synthetic MR may be used for classifying different types of brain tumors.