MRI derived brain structural measurements from multicenter datasets can strongly be affected by factors such as the acquisition protocol, the static magnetic field strength and the scanner manufacturer. A preliminary study was performed to assess the homogeneity of population metrics from 3DT1 scans acquired with already established routine protocols in a dataset of 174 healthy subjects from 18 Italian Research Hospital Centers (IRCCS). The impact of each center acquisition parameters on outcomes was assessed with quality control measurements and FreeSurfer volumetric metrics of cortical and subcortical structures. Future multicenter studies will benefit from harmonizing the acquisition protocols.
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