Abstract #3139

Multimodal 7T MRI of epilepsy surgery candidates: Prospective evaluation of impact on presurgical decisions

Giske Opheim^1,2, Melanie Ganz-Benjaminsen^1,3, Patrick Fisher¹, Ulrich Lindberg⁴, Mark Bitsch Vestergaard⁴, Helle Juhl Simonsen⁴, Henrik Bo Wiberg Larsson⁴, Anne-Mette Leffers⁵, Camilla Gøbel Madsen⁵, Olaf Bjarne Paulson¹, and Lars Hageman Pinborg^1,2

¹Neurobiology Research Unit, Dept. of Neurology, Rigshospitalet, Copenhagen, Denmark, ²Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, ³Dept. of Computer Science, University of Copenhagen, Copenhagen, Denmark, ⁴Functional Imaging Unit, Dept. of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet - Glostrup, Copenhagen, Denmark, ⁵Dept. of Diagnostic Radiology, Centre for Functional & Diagnostic Imaging and Research, Hvidovre Hospital, Copenhagen, Denmark

Identifying lesions at 3T MRI remains the most important correlate to epilepsy surgery outcome. Since 45% of candidates present with negative 3T MRI, investigation of diagnostic yield of clinical 7T MR protocols along with post-processing markers is urged. This ongoing study will evaluate how radiological descriptions and computational morphometrics affect presurgical decisions. So far, 19 patients and 31 controls are scanned at the Philips Achieva 7T system at Hvidovre Hospital, Denmark. Preliminary analyses of automatic segmentations show promising potential. We are in radiological training, but expect first case with evaluation of impact on presurgical decision to start around new-year 2018/2019.

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