Abstract #3243

Intracranial Vessel Wall Imaging: Artifactual Effects of Localized Movement and In-line Mitigation with Self-gating

Zhehao Hu^1,2, Fei Han³, Qi Yang^1,4, Shlee Song⁵, Marcel Maya⁶, Anthony Christodoulou^1,7, Xiaoming Bi³, Debiao Li^1,2,8, and Zhaoyang Fan^1,2,8

¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ²Department of Bioengineering, University of California, Los Angeles, CA, United States, ³Siemens Healthcare, Los Angeles, CA, United States, ⁴Department of Radiology, Xuanwu Hospital, Beijing, China, ⁵Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ⁶Department of Imaging, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ⁷Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ⁸Department of Medicine, University of California, Los Angeles, CA, United States

Intracranial vessel wall imaging can directly visualize the vessel wall and characterize wall pathologies, and has drawn great clinical interest. 3D variable-flip-angle turbo spin-echo is currently the method of choice for intracranial VWI. However, because of its 3D acquisition fashion, this method is inherently susceptible to motion as previously shown in extracranial VWI studies. For intracranial VWI, motion may also result from bulk or localized movement, although the former can be effectively reduced by using foam pads. Reducing motion degradation becomes more critical because of long scan time and demanding spatial resolution. This work aims to investigate the effect of localized movement on intracranial VWI quality and to present an in-line self-gating approach to mitigate quality deterioration.

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