A multiparametric quantitative white matter study using MRI was designed to include 15 relapsing remitting MS patients and 10 age and sex matched controls. The imaging protocol acquired 3D conventional imaging, SWI, QSM, DTI, MTC, and STrategically Acquired Gradient Echo (STAGE) imaging. ROI were manually drawn around MS lesions in T2-FLAIR and QSM. Contralateral normal appearing white matter (NAWM) and NAWM in controls were drawn in all modalities to measure mean intensity and volume. We found a good correlation between QSM, MTR, FA, MWF and conventional imaging. QSM’s sensitivity to demyelination best complimented T2-FLAIR’s sensitivity to inflammation and scarring.