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Abstract #3346

Multi-shot Diffusion EPI Reconstruction with Iterative Rigid Motion-correction and Motion-induced Phase-correction for Brain Imaging

Malte Steinhoff1, Kay Nehrke2, Alfred Mertins1, and Peter Börnert2,3

1Institute for Signal Processing, University of Lübeck, Lübeck, Germany, 2Philips Research Hamburg, Hamburg, Germany, 3Dept. Radiology, LUMC, Leiden, Netherlands

Multi-shot diffusion-weighted imaging offers increased SNR and higher resolution, but makes the acquisition vulnerable to shot-specific phase variations and macroscopic inter-shot motion. A wide range of iterative phase-corrected reconstruction schemes have been proposed to overcome the inter-shot phase inconsistencies, but robust motion estimation is still challenging due to the inherently low SNR of DWI. This work moves forward from initial one-time rigid motion estimation to an alternating optimization balancing the joint image, phase and motion estimation. A novel multi-shot echo-planar diffusion algorithm with iterative motion and phase correction is presented in simulations and in-vivo.

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