Meeting Banner
Abstract #3419

Brain White Matter Abnormality Induced by Chronic Spinal Cord Injury in the Pediatric Population: A Tract Based Spatial Statistic Study

Joshua Fisher1, Mahdi Alizadeh1, Devon Middleton1, Caio Matias1, MJ Mulcahey1, Feroze Mohamed1, and Laura Krisa1

1Thomas Jefferson University, Philadelphia, PA, United States

Few studies have quantified the change in cortical white matter tracts following chronic spinal cord injury in a pediatric population. Additionally, no work has been done to compare chronic SCI subjects with different American Spinal Injury Association Impairment (AIS) scale classifications. We hypothesized that these cortical changes can be detected using tract-based spatial statistics (TBSS). Our efforts revealed that significant changes in fractional anisotropy occur in several motor and sensory related regions. We conclude that TBSS can be effectively used to identify alterations in brain microstructure in a chronic pediatric spinal cord injury population.

This abstract and the presentation materials are available to members only; a login is required.

Join Here