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Abstract #3520

Diffusion-Weighted ZOOM-EPI with Simultaneous Multi-Slice Imaging

J├╝rgen Finsterbusch1 and Caspar Florin1

1Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Zonal oblique multi-slice (ZOOM) EPI uses cross-sectional RF excitations to focus the measurement volume to a small, inner volume which allows to reduce the FOV without aliasing in the phase-encoding direction. Thus, geometric distortions are reduced and the spatial resolution of diffusion-weighted acquisitions can be increased as has been demonstrated for the optic nerve and spinal cord. In this study, ZOOM-EPI is combined with simultaneous multi-slice (SMS), the boundary condition to avoid unwanted signal contributions is determined, and the feasibility to shorten acquisitions times is demonstrated for diffusion-tensor imaging (DTI) of the human spinal cord.

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