Detection of degenerative cervical spinal cord compression (DCSCC) at early stage that causes spinal cord (SC) microstructure disruption is limited when current imaging techniques are used. Early detection of damage to SC can predict symptomatic degenerative cervical myelopathy (DCM). We are presenting novel HARDI-ZOOMit protocol (High Angular Resolution Diffusion Imaging + syngo ZOOMit sequence), which is able to detect changes in microstructural diffusion MRI (dMRI) parameters (e.g. fractional anisotropy – FA, mean diffusivity – MD) in asymptomatic DCSCC. Results obtained with HARDI-ZOOMit protocol reveal higher sensitivity when compared to clinical RESOLVE (REadout Segmentation Of Long Variable Echo trains) protocol.