Abstract #3622

Assessing inter-vender reproducibility of diffusion tensor imaging of the spinal cord for multi-center imaging studies

Mitsuhiro Kitamura¹, Satoshi Maki¹, Takeo Furuya¹, Takuya Miyamoto¹, Yasuhiro Shiga¹, Kazuhide Inage¹, Sumihisa Orita¹, Koji Matsumoto², Shingo Terakado³, Yoshitada Masuda², and Seiji Ohtori¹

¹Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba City, Japan, ²radiology, Chiba University Hospital, Chiba City, Japan, ³radiology, Asahi General Hospital, Asahi City, Japan

In this study, we assessed the inter-vendor precision of diffusion tensor imaging (DTI) metrics using consensus acquisition protocol across 3T scanners from 3 main vendor at the two sites. The data were acquired from the traveling human healthy volunteer. DTI data and anatomical images were also acquired and imaging data were processed using the Spinal Cord Toolbox (SCT). Relatively higher inter vender reproducibility of fractional anisotropy (FA) in and cross-sectional area were demonstrated and it is considered feasible to conduct multicenter DTI studies of the spinal cord using FA value as biomarker and SCT as postprocessing tool.

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