Quantifying tissue T1 and T2 provides valuable biomarker for characterizing various tissue pathologies yet limits by its long scan time and consequently hampered their clinical practice. Magnetic resonance image compilation (MAGiC) and Magnetic resonance fingerprinting (MRF) are novel imaging techniques that simultaneously provide quantitative maps of tissue relaxation times at one acquisition. We compared the quantitative values in various brain tissue using the MAGiC and MRF in healthy volunteers. In quantifying T1 between two techniques, no significant difference was found in white matter and gray matter, but difference was observed in cerebrospinal fluid. On the contrary, T2 value showed significant difference.