Meeting Banner
Abstract #3795

Detecting CBF to Explore Verbal Memory Impairment Mechanisms in Subcortical Stroke Patients

Caihong Wang1, Peifang Miao1, Sen Wei2, Kaiyu Wang3, and Jingliang Cheng1

1Department of MRI, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 3GE Healthcare MR Research, Beijing, China

In order to explore the neural substrates underlying verbal memory (VM) impairment in subcortical stroke patients, we recruited sixty patients with chronic subcortical stroke and sixty normal controls. 3D-ASL imaging was used to measure the resting-state values of voxel-wise cerebral blood flow (CBF) and the alterations of functional covariance network were detected. In this study, the different CBF levels in the stroke patients and the normal controls, as well as the close correlation between the CBF values and the VM scores, indicate that the VM impairment in stroke patients may be associated with the disconnection of frontal-lobe network.

This abstract and the presentation materials are available to members only; a login is required.

Join Here