The measurement of R1rho (1/T1rho) spectrum and its asymmetry have several advantages over Chemical Exchange Saturation Transfer (CEST) to probe chemical exchange effect. However, these approaches suffer from B1 Radiofrequency (RF) and B0 field inhomogeneities. In this work, we proposed a new approach to perform robust R1rho asymmetry measurement using adiabatic spin-lock RF pulse and demonstrated its potential to probe metabolites.
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