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Abstract #4059

Joint placental angiography with perfusion and apparent oxygenation mapping

Laurence H Jackson1, Jana Hutter1, Anthony N Price1, Alison Ho2, Laura McCabe1,3, Thomas A Roberts1, Maria Deprez1, Lucy Chappell2, Mary Rutherford1,3, Enrico De Vita1, and Joseph V Hajnal1,3

1Biomedical Engineering,School of Biomedical Engineering & Imaging Sciences, Kings College London, London, United Kingdom, 2Department of Women and Children’s Health, School of Life Course Sciences, Kings College London, London, United Kingdom, 3Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, Kings College London, London, United Kingdom

In this work we combine two novel methods for imaging the oxygen transfer system between maternal and fetal circulations, 1) a motion robust angiography acquisition and 2) a combined perfusion and oxygenation acquisition. This enables the matching of functional regions of placenta to the vessels that supply them in utero. This may provide further insight into the vascular origins of major obstetric diseases such as fetal growth restriction and pre-eclampsia.

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