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Abstract #4081

Real-Time Imaging during Free Breathing for Patient-Friendly V/Q Scan of the Whole Lung in One Minute at 3T

Andreas Voskrebenzev1,2, Till Kaireit1,2, Marcel Gutberlet1,2, Filip Klimes1,2, Lea Behrendt1,2, Christoph Forman3, Frank Wacker1,2, and Jens Vogel-Claussen1,2

1Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, 2Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany, 3Magnetic Resonance, Siemens Healthcare GmbH, Erlangen, Germany

MRI techniques like phase-resolved functional lung imaging (PREFUL) offer the possibility for pulmonary ventilation (V) / perfusion (Q) imaging without ionizing radiation or contrast agents. One major drawback of such methods is the long acquisition time, if a whole lung coverage is required. In this study, five healthy volunteers were scanned with a highly accelerated 2D multi-slice real-time PREFUL (RT-PREFUL) acquisition with compressed sensing and parallel imaging reconstruction to establish a V/Q scan of the whole lung in one minute. The comparison with conventional PREFUL technique showed very similar ventilation results and comparable perfusion results with 9-fold acceleration.

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