Meeting Banner
Abstract #4094

Quantitative Pulmonary Ventilation Imaging in Patients with Cystic Fibrosis using breath-hold 3D-UTE at 3T

Simon Veldhoen1, Julius Frederik Heidenreich1, Andreas Max Weng1, Tobias Wech1, Florian Segerer2, Helge Uwe Hebestreit2, Thomas Benkert3, Josef Pfeuffer3, Thorsten Alexander Bley1, and Herbert Köstler1

1Department of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany, 2Department of Pediatrics, Universtiy Hospital Würzburg, Würzburg, Germany, 3Application Development, Siemens Healthcare GmbH, Erlangen, Germany

We demonstrate first results of breath-hold 3D-UTE MRI for ventilation imaging in CF patients. Ten patients underwent 3D-UTE MRI of the lungs. Data were acquired in breath-hold for 5 different breathing states, in order to obtain information regarding the ventilation. 3D-UTE MRI provided sufficient morphologic image quality for the detection of structural lung disease and site-resolved information regarding pulmonary ventilation. Ventilation measurements correlated well with parameters of conventional lung function testing and were in accordance with pulmonary ventilation measured with techniques published recently. The technique could be an innovative method able to enhance diagnosis and monitoring of structural lung disease.

This abstract and the presentation materials are available to members only; a login is required.

Join Here