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Abstract #4103

Investigating the feasibility of performing quantitative DCE-MRI in an abbreviated breast examination

Kalina P Slavkova1, Julie C DiCarlo2, Anum K Syed3, John Virostko4, Anna G Sorace4, and Thomas E Yankeelov2,3,4

1Physics, University of Texas at Austin, Austin, TX, United States, 2Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, United States, 3Biomedical Engineering, University of Texas at Austin, Austin, TX, United States, 4Diagnostic Medicine, University of Texas at Austin, Austin, TX, United States

MRI is the most sensitive imaging modality for detecting breast cancer, but its use as a screening tool is limited. There has been recent interest in developing an “abbreviated” breast MRI protocol as a screening protocol, which involves a significantly shorter breast MRI exam that does not compromise diagnostic accuracy. In this work, we evaluate the accuracy of estimating perfusion parameters from dynamic contrast-enhanced MRI data by truncating the data into a series of abbreviated-time courses and comparing the corresponding parameter estimates to the original, full-time course parameter estimates.

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