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Abstract #4303

In-Vivo Metabolism Differences of Multiple Body Parts using Hyperpolarized [2-13C]pyruvate

Jian-Xiong Wang1

1UT Southwestern Meidcal Center, Dallas, TX, United States

Hyperpolarized [2-13C]-pyruvate can assess multiple metabolic pathways within mitochondria to follow the 13C label beyond flux through PDH complex and investigate the incorporation of acetyl-coenzyme into different metabolic pathways. This study investigated metabolic products from [2-13C]-pyruvate and the differences of LDH and ATL process in heart, liver and kidney.

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