The development of heteronuclear magnetic resonance imaging is one of the strategies in a control of a biodistribution of therapeutic agents. Molecules containing 19F atoms are particularly attractive for use as MRI markers due to favorable physical properties of fluorine nucleus. Advances in MRI instrumentation and ultrafast pulse sequence development expanded the range of fluorine compounds available as new MRI markers. Optimization of imaging parameters of such sequences enables the visualization of 19F compounds with the less preferable characteristic. In this paper, we report the application of the 3D UTE sequence at a high field for imaging of compounds with a complex 19FNMR spectrum and very short T2.
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