Abstract #4485

Reconstruction-based Super-Resolution for High-Resolution Abdominal MRI: A Preliminary Study

Michael Ebner^1,2, Premal A Patel¹, David Atkinson³, Lucy Caselton³, Stuart Taylor³, Alan Bainbridge⁴, Sebastien Ourselin^1,2, Manil Chouhan³, and Tom Vercauteren^1,2

¹Wellcome / EPSRC Centre for Interventional and Surgical Sciences, University College London, London, United Kingdom, ²School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ³Centre for Medical Imaging, University College London, London, United Kingdom, ⁴Department of Medical Physics, University College London Hospitals NHS Trust, London, United Kingdom

Magnetic resonance (MR) cholangio-pancreatography (MRCP) is an established specialist method for imaging the upper abdomen and biliary/pancreatic ducts. Due to limitations of either MR image contrast or low through-plane resolution, patients may require further evaluation with contrast-enhanced computed tomography (CT) images. However, CT fails to offer the high tissue-ductal-vessel contrast-noise ratio available on T2-weighted MRI. MR Super-Resolution Reconstruction (SRR) frameworks can provide high-resolution visualizations from multiple low through-plane resolution single-shot T2-weighted (SST2W) images as currently used during MRCP studies. Here, we investigate the clinical potential of using additional SST2W acquisitions in multiple directions with SRR for higher diagnostic yield.

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