Abstract #4490

Effects of Image Registration in Dynamic Contrast-Enhanced MRI of the TMJ

Lea Sjurine Starck^1,2, Erling Andersen^2,3, Ondřej Macíček⁴, Oskar Angenete^5,6, Thomas Augdal⁷, Erlend Hodneland^2,8, Radovan Jiřík⁴, Karen Rosendahl^9,10, and Renate Grüner^1,2,7

¹Dept. of Physics and Technology, University of Bergen, Bergen, Norway, ²Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Bergen, Norway, ³Dept. of Clinical Engineering, Haukeland University Hospital, Bergen, Norway, ⁴Institute of Scientific Instruments, Czech Academy of Sciences, Brno, Czech Republic, ⁵Dept. of Radiology and Nuclear Medicine, St. Olav hospital HF, Trondheim, Norway, ⁶Dept. of Circulation and Medical Imaging, Norwegian university of Science and Technology, Trondheim, Norway, ⁷Dept. of Radiology, University Hospital of North Norway, Tromsø, Norway, ⁸Norse, Bergen, Norway, ⁹Dept. of Radiology, Haukeland University Hospital, Bergen, Norway, ¹⁰Dept. of Clinical Sciences, University of Bergen, Bergen, Norway

The effect of elastic and affine motion correction in dynamic contrast enhanced MRI ofthe temporomandibular joints in children is investigated. Imaging in children is particularly difficultdue to motion. This hampers DCE-MRI and pharmacokinetic estimations for their potentialdiagnostic value in these children with Juvenile Idiopathic Arthritis with possible TMJ involvement.The relative enhancement curves obtained with different motion correction approaches arecompared with the curves calculated with the Gamma Capillary Transit Time model. It is found thatwhen image registration is applied, a greater number of participants can be analysed. The elasticmotion correction approach outperforms the affine approach.

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