Neuronal current mapping using MRI has profound biomedical applications, but is hampered by limited temporal resolution. Using a technique known as Sub-Millisecond Imaging of cycLic Event or SMILE, we demonstrate that the temporal resolution of MRI can be substantially increased to the sub-millisecond scale or shorter. This allows capturing ultra-fast physical or biological processes that are cyclic. Although our experimental studies are limited to mapping time-varying currents in a phantom, the same concept can be extended to capturing more complex biological processes, including but not limited to, neuronal currents.
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